Melancholia

"Ich steh mit einem Fuß im Grabe"


(I am standing with one foot in the grave),

Monday, September 25, 2017

The Hollow Men: What the end of the world looks like...




What the end of the world looks like...


The Hollow Men

This is the way the world ends
This is the way the world ends
This is the way the world ends
Not with a bang but a whimper.

by T. S. Eliot Written 1925




 

Monday, July 10, 2017

Rolling Stones and Howlin Wolf _1965_ How Many More Years

Song Lyrics: How Many More Years



How many more years, have I got to let you dog me around

How many more years, have I got to let you dog me around

I'd soon rather be dead, sleeping six feet in the ground



I'm gonna fall on my knees, I'm gonna raise up my right hand

I'm gonna fall on my knees, I'm gonna raise up my right hand

Say I'd feel much better darling, if you'd just only understand



I'm going upstairs, I'm gonna bring back down my clothes

I'm going upstairs, I'm gonna bring back down my clothes, do them all

If anybody ask about me, just tell'em I walked out on




  





Monday, June 19, 2017

Great Ladies Of Jazz - Great Female Vocal Jazz


 
Great Ladies Of Jazz – Great Female Vocal Jazz

Find the album here: http://bit.ly/1yrg7uh http://amzn.to/1v0rLrZ http://bit.ly/1rkBerD ,http://bit.ly/1oi6Yud http://bit.ly/1rmlWFm

00:00 - Sarah Vaughan – Pennies from Heaven
03:05 - Billie Holiday - Don't Explain
06:30 - The Andrews Sisters - In the Mood
09:23 - Alma Cogan - Make Love to Me
11:48 - Kay Starr - I've Got the World On a String
13:38 - The Boswell Sisters - Old Yazoo
16:54 - Mildred Bailey - I'm Nobody Baby
19:53 - Eartha Kitt - C'est si bon
22:52 - Nellie Lutcher - That'll Just About Knock Me Out
25:24 - Betty Roche - Take the A Train
33:24 - Marlene Dietrich - You Go to My Head
36:32 - Ethel Merman - I Get a Kick Out of You
39:41 - Lena Horne - Stormy Weather
43:04 - Carmen Miranda - The Lollypop Song
45:30 - Billie Holiday - Body and Soul
48:27 - The Andrews Sisters - Rum and Coca Cola
51:39 - Helen Forrest - Mary Had a Little Lamb
54:28 - Chris Connor - I Hear Music
56:30 - Betty Carter - Social Call
59:29 - Helen Humes - You're Drivin' Me Crazy
01:02:40 - Nancy Wilson - Born To Be Blue
01:04:57 - Blossom Dearie - The Doodlin Song

JazzAndBluesExperience
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  • Category: Music


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J,D. LOUDERMILK





Published on Jul 2, 2012
Dedicated to all my Native American friends here on YT and beyond. Always loved these lyrics. Very powerful.



Indian Reservation

John Loudermilk


They took the whole Cherokee nation
Put us on this reservation

Took away our ways of life
The tomahawk and the bow and knife

Took away our native tongue
And taught their English to our young

And all the beads we made by hand
Are nowadays made in Japan

Cherokee people, Cherokee tribe
So proud to live, so proud to die

They took the whole Indian nation
Locked us on this reservation

Though I wear a shirt and tie
I'm still part redman deep inside

Cherokee people, Cherokee tribe
So proud to live, so proud to die

But maybe someday when they learn
Cherokee nation will return, will return, will return, will return, will return
  • Category: Music
  • License: Standard YouTube License



Indian Reservation - Orlando Riva Sound | Full HD |

Monday, April 24, 2017

Warren Buffett Learned a Useful Skill to Overcome a Weakness


Confront your weaknesses and commit to finding solutions:

 Warren Buffett was born with a fear of public speaking. But he didn't let that hold him back from his dreams.
 *Image from Fortune Live Media, Flickr

 

One Skill That Helped Warren Buffett  Thrive

April 12, 2017


Warren Buffett has two college degrees, a bachelor’s degree from the University of Nebraska-Lincoln and a master’s degree from Columbia Business School. And yet, only one diploma hangs on his wall: his certificate for graduating from a Dale Carnegie public speaking course.

Despite his education and early success, Warren had an innate fear of public speaking.
 
To address his fear of speech making, he enrolled in a Dale Carnegie public speaking course.

After learning some “psychological tricks” and being forced to speak in front of the class over and over again, Buffett finally got comfortable speaking in front of an audience.

Today, Buffett conducts countless radio and television interviews and gives speeches across the world, while also serving as CEO of a business with more than 350,000 employees. All of which require strong public speaking skills, and all of which are integral to him becoming one of the richest people in the world.

The process Warren Buffett followed to empower himself with new communication skills:         :

1. he identified an area of weakness that was holding him back – public speaking. 
  
2.  he took time out of his day to learn that skill, which would help him throughout the rest of his career.
 
It took his commitment to identify and to overcome a fear of speech making, time out of his day to learn new skills and to practice them. 





Murali Coryell - Softly Let Me Kiss Your Lips


 
Album: Eyes Wide Open
http://www.muralicoryell.com/
Murali
is a triple threat contemporary blues artist who can sing, write and
play guitar with the best in the business. As the son of guitar legend
Larry Coryell, Murali grew up around the likes of Jimi Hendrix, Miles
Davis, & Carlos Santana.


 

Tin Pan - Evening



  
Published on Feb 20, 2017
Album:The Home Bartender's Song Book 2011
Tin Pan: http://tinpanband.com/wordpress/?page...
https://www.amazon.com/Home-Bartender...
-----------
Lyrics:
Evening, every night you come and you find me
Why must you always remind me, that my baby's gone
Evening, you got me deeper in your power
Every minute seems like an hour
Since my baby's gone
Shadows fall upon the wall
That's the time I miss your kisses most of all
Even though I try, how can I go on
Oh evening, let me sleep 'til the glow of dawn is breaking
I don't care if I don't awaken
Since my baby's gone
Shadows fall upon the wall
That's the time I miss your kisses most of all
Even though I try, how can I go on
Oh evening, let me sleep 'til the glow of dawn is breaking
I don't care if I don't awaken
Since my baby's gone
----









Wednesday, April 19, 2017

Quotes by Aristotle Onassis

Listed below are some of his most famous quotes:
  1. At your job you must be serious but at life you must be crazy.
  2. If there weren’t any women all the money in the world wouldn’t matter.
  3. Never start a job, a battle, or a relationship, if the fear of losing overshadows the prospect of success.
  4. Take care of your body. Be as good as you can with it. Don’t mind the details. Look at me, I look nothing like a Greek God, but I never wasted my time crying over the bad aspects of myself, remember things are only as bad as you think they are.
  5. Every win is an injustice to someone.
  6. The secret in business is knowing something nobody else knows.
  7. The rule is there is no rules.
  8. Be either rich or an enemy of the rich. I understand both, but never be envious of the rich and try to please them at the same time.
  9. After a point, and so on, money stops to matter, it stops being the goal, the game is all that matters.
  10. To be happy make sure you are tanned, live in expensive buildings, even if you have to stay in the cellar, go out to expensive restaurants, even if you can only afford one drink and if you have to borrow, borrow a lot.
  11. Crises give birth to moguls.
  12. I don’t have friends or enemies, I have competitors.
  13. It is in our darkest moments where we have to focus to see the light.
  14. You will understand that if you make things easier for others you will earn their liking.
  15. If someone is mediocre he will pass by unnoticed, if he is outrageously successful, he is suspicious.
  16. To be successful you have to act big, think big, and talk big.
  17. My law in business is to be the one buying not selling.
  18. The more you have the more you know you don’t have.
  19. I made a big mistake. I never believed that in the world we live in, emotions can overcome every logic in business.
  20. The best deals and the best sex happens outside of boundaries.
- See more at: http://greece.greekreporter.com/2015/11/23/famous-quotes-by-aristotle-onassis/#sthash.6xuA2s73.dpuf 










FOREVER MY DARLING AaRON NEVILLE


 



I'll Stand by You ( LIVE ) Chrissie Hynde


 





linda ronstadt and the stone ponys - different drum (1967)


 





The Pretenders' Chrissie Hynde in studio q




Published on Sep 8, 2015
Chrissie
Hynde, lead singer of The Pretenders, has one of the most distinctive
voices in rock — but her personal story and strong opinions would also
stand out in any crowd. The Don't Get Me Wrong singer joins Shad to
discuss her revealing new memoir, Reckless: My Life as a Pretender.



Chrissie Hynde: http://chrissiehynde.com/

Subscribe: http://www.youtube.com/subscription_c...

q's Homepage: http://www.cbc.ca/q

q on Twitter: https://twitter.com/cbcradioq

q on Facebook: https://www.facebook.com/QonCBCRadio



q
is a magazine show that’s unpredictable in the best sense - proud to be
“a wild mix of culture by way of Canada” as described by the New York
Times. The Globe & Mail noted the show’s “raging popularity across a
variety of platforms -- podcasts, television, websites, satellite
radio, terrestrial radio, and occasional live remote broadcasts."



Tuesday, April 18, 2017

Gabor Szabo - Spellbinder (1966) [full album]


 
Published on Jul 8, 2014
Unique Music from the terribly underrated Gabor Szabo.

01 - Spellbinder (0:00)
02 - Witchcraft (5:30)
03 - It Was A Very Good Year (10:12)
04 - Gypsy Queen (13:00)
05 - Bang Bang (My Baby Shot Me Down) (18:17)
06 - Cheetah (20:47)
07 - My Foolish Heart (24:59)
08 - Yearning
09 - Autumn Leaves
10 - Speak To Me Of Love



 

Linda Ronstadt's amazing cover of Patsy Cline's Crazy



Uploaded on Dec 13, 2011
Okay,it
was 1976, no one was thinking of Patsy. She was far from being the icon
she has been for the last 30 years. But at that time, Linda introduced
this as Willie Nelsons song. the arrangement is superb with the country
guitar lead, terrrific acoustic guitar and Linda's amazing vocal, esp in
the closing part of the song.



Sunday, April 16, 2017

Albert Camus's “The Human Crisis” read by Viggo Mortensen, 70 years later



 



00:20 Introduction by Shanny Peer, Director of the Maison Française
05:35 Introduction by Alice Kaplan, Professor of Yale University
11:50 Reading of 'The Human Crisis' by Viggo Mortensen
56:50 Discussion with Viggo Mortensen, Alice Kaplan and Souleymane Bachir Diagne

On
April 28, 2016 a reading by Viggo Mortensen of a speech by Albert
Camus, and roundtable discussion with Viggo Mortensen, Alice Kaplan and
Souleymane Bachir Diagne

Albert Camus originally delivered this
lecture on “La Crise de l’homme” on March 28, 1946, to a very full house
at the McMillin Academic Theatre at Columbia University, on his first
and only trip to the United States. 70 years later, to celebrate
Camus’s visit to New York and Columbia, his lecture will be delivered in
a dramatic reading by the actor Viggo Mortensen, in a version newly
translated into English by Alice Kaplan.

The event will be
introduced by Shanny Peer and by Alice Kaplan, who will share new
research from her forthcoming book, Looking for the Stranger: Albert
Camus and the Life of a Literary Classic, to bring alive Camus’ U.S.
visit and provide a context for his lecture. After the reading, Bachir
Diagne and Alice Kaplan will be joined by Viggo Mortensen for a panel
discussion about Albert Camus’ influence, his impressions of the U.S.,
and his reception in this country as a leading voice of the postwar
generation of French intellectuals.

Participants: Viggo Mortensen
has consistently earned acclaim for his work in a wide range of films.
Some of these include Jauja, Loin des hommes, The Two Faces of January, A
Dangerous Method, The Road, Eastern Promises, Appaloosa, A History of
Violence, and The Lord of the Rings trilogy. He has received various
nominations and awards from groups including the Screen Actors Guild,
the American Academy of Motion Picture Arts and Sciences, the Hollywood
Foreign Press Association, and the British Academy of Film and
Television Arts. Apart from acting in movies and plays, Mortensen is a
poet, photographer, and painter. He founded and is the editor of
Perceval Press, an independent publishing house specializing in poetry,
photography, painting, and critical writing.

Souleymane Bachir Diagne is Professor of Philosophy and French and Chair, Department of French, Columbia University.

Alice Kaplan is the John M. Musser Professor of French and chair of the Department of French at Yale University.

This
event is organized in partnership with The Albert Camus Estate and is
part of a series of events taking place in New York on the theme of
"Camus : A Stranger in the City" (March 26 – April 19 / @camusnyc2016)
commemorating the 70th year anniversary of Camus’ visit to the United
States.

If you want to see the Q&A with Viggo Mortensen about the movie Far from Men, a video is available here: https://youtu.be/GE3Ux2on5B0?t=2m20s

Columbia Maison Française website: http://maisonfrancaise.org/
Follow us on FB: https://www.facebook.com/columbia.mai...
Twitter and Instagram: Columbia_MF

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  • License

    • Standard YouTube License




Link: https://youtu.be/aaFZJ_ymueA






Wednesday, April 12, 2017

Patti Page - Tennessee Waltz (Original Classic with Lyrics)


 






Tennessee Waltz ( 1959 ) - CONNIE FRANCIS - Lyrics



I ♥ Oldies

Tennessee Waltz ( 1959 ) - CONNIE FRANCIS - Lyrics

Written in 1946, first release in 1948.

I was waltzin' with my darlin' to the Tennessee Waltz

When an old friend I happened to see

Introduced her to my loved one

And while they were waltzinn'

My friend stole my sweetheart from me

I remember the night and the Tennessee Waltz

Now I know just how much I have lost

Yes, I lost my little darlin' the night they were playing

The beautiful Tennessee Waltz



S.Vansay ( Vanhxay )




Linda Ronstadt & Smokey Robinson - Ooo Baby Baby / The Track Of My Tears...


































Published on Oct 11, 2015
Duet
of Linda Ronstadt and Smokey Robinson performing his soul R&B hits
Ooo Baby Baby and The Track Of My Tears before a live studio audience at
the Pasadena Civic Auditorium in Pasadena, California on March 25,
1983. "Ooo Baby Baby" and "The Track Of My Tears" were written and
recorded on Motown Records by Smokey Robinson by The Miracles in 1965.
Two of the Miracles' most-covered tunes, Linda Ronstadt achieved Ooo
Baby Baby's greatest commercial success when she covered it in 1978;
then The Track Of My Tears on her 1976 album Prisoner In Disguise.



Tuesday, April 11, 2017

Friday, April 7, 2017

Sittin' On The Dock Of The Bay | Playing For Change | Song Around The World


 




FOREVER MY DARLING AaRON NEVILLE


 

Norah Jones Live Amsterdam 2007 - FULL CONCERT HQ - AMAZING FULL LIVE !!!


  
Thinking About You, Sinkin' Soon (3:40), Not My Friend (7:45), Sunrise (10:45), Until The End (14:15), Creepin' In (18:40), Humble Me (23:35), My Dear Country (28:20), Rosie's Lullaby (32:15), Be My Somebody (36:30), Don't Know Why (40:15), Come Away With Me (44:40).



 

Norah Jones Greatest Hits - Norah Jones Full Album 2017


 





Best Songs Of Norah Jones - Norah Jones Greatest Hits 2017








Monday, April 3, 2017

Addictive behavior



  • Does your sibling have an addiction? Your well-being needs to be a priority before you can truly help them.


    I had a black dog, his name was depression


      

    At
    its worst, depression can be a frightening, debilitating condition.
    Millions of people around the world live with depression. Many of these
    individuals and their families are afraid to talk about their struggles,
    and don't know where to turn for help. However, depression is largely
    preventable and treatable. Recognizing depression and seeking help is
    the first and most critical towards recovery.

    In collaboration
    with WHO to mark World Mental Health Day, writer and illustrator Matthew
    Johnstone tells the story of overcoming the "black dog of depression".
    More information on the book can be found here: http://matthewjohnstone.com.au/

    For more information on mental health, please visit: http://www.who.int/topics/mental_heal...

    Disclaimer:
    This video may contain links and references to third party-websites.
    WHO is not responsible for, and does not endorse or promote, the content
    of any of these websites and the use thereof.



    "Scotland Is Her Name", sung by (Jacquie Holland) Albannach


    A beautiful song sung by Jacquie Holland, written by Jamesie Johnson both
    of Albannach. I have put a wee film together round the fabulous words.
    • Albannach, Gaelic for "Scottish" or "Scotsman", is a Scottish band. Their traditional music is heavily percussive, driven by bass drums, bodhráns and a single bagpipe. From the first, eponymous album in 2006, Albannach has promoted a sentiment of Scottish patriotism in songs such as "Uprising," a tribute to famed patriot William Wallace; they have covered songs like "1320" by Scottish folk artist Gordon Menzies of the band Gaberlunzie. Several songs on early albums referred to the Island of Barra, the Outer Hebrides home of Albannach's bagpiper, Donnie MacNeil. Vocal songs that survive in the touring repertoire are sung either a cappella or with minimal accompaniment, emphasizing their lyrics. Examples of these include "Scotland is Her Name" and "Peaceful is the Glen"; the latter commemorates the Massacre of Glencoe, while the former is more directly topical and even political in its implied support for an independent Scotland. With these exceptions, the bulk of the touring repertoire, and of the band's discography, remains instrumental.{https://en.wikipedia.org/wiki/Albannach_(band)}

      Category: Travel + Events

    • Standard YouTube License

    SCOTLAND THE BRAVE ~ PIPES & DRUMS ~ ( HD )




    "Scotland the Brave" (Gaelic: Alba an Aigh).. A view of the amazing Scottish country taken from across Scotland.

    The sunsets are enhanced by digital editing.
    Accompanied by the music Scotland The Brave.
    Performed by The Pipes & Drums of The Royal Tank Regiment. from the CD .
    The Complete Scottish Bagpipe Collection.
    Available @ itunes
    I hope you enjoy viewing :)

    Scotland the Brave
    Lyrics

    Hark when the night is falling
    Hear! Hear the pipes are calling,
    Loudly and proudly calling,
    Down thro' the glen.
    There where the hills are sleeping,
    Now feel the blood a-leaping,
    High as the spirits of the old Highland men.

    Towering in gallant fame,
    Scotland my mountain hame,
    High may your proud standards gloriously wave,
    Land of my high endeavour,
    Land of the shining river,
    Land of my heart for ever,
    Scotland the brave.

    High in the misty Highlands,
    Out by the purple islands,
    Brave are the hearts that beat
    Beneath Scottish skies.
    Wild are the winds to meet you,
    Staunch are the friends that greet you,
    Kind as the love that shines from fair maiden's eyes.

    Towering in gallant fame,
    Scotland my mountain hame,
    High may your proud standards gloriously wave,
    Land of my high endeavour,
    Land of the shining river,
    Land of my heart for ever,
    Scotland the brave.

    Far off in sunlit places,
    Sad are the Scottish faces,
    Yearning to feel the kiss
    Of sweet Scottish rain.
    Where tropic skies are beaming,
    Love sets the heart a-dreaming,
    Longing and dreaming for the homeland again.

    Towering in gallant fame,
    Scotland my mountain hame,
    High may your proud standards gloriously wave,
    Land of my high endeavour,
    Land of the shining river,
    Land of my heart for ever,
    Scotland the brave.

    Dropkick Murphys - Auld Lang Syne


    Should old acquaintance be forgot
    and never brought to mind?
    Should old acquaintance be forgot
    in the days of auld lang syne?



    Sunday, April 2, 2017

    Andre Rieu - Scotland The Brave - Amazing Grace


      
    Andre Rieu - Scotland The Brave - Amazing Grace

    Mull of Kintyre


      
    Link:












    Uploaded on Oct 9, 2008
    The Rhine Area Pipes & Drums - Duesseldorf
    http://www.rapd.de/

    Drum Major: Jürgen Uhrig

    »Military Music Festival Cologne 2004«

    After
    an intensive training with experts from the BAOR (British Army of the
    Rhine) the German bagpipe band was founded in 1977. The band's public
    appearances help to make the scottish bagpipes more popular in Germany.

    The
    song was written by Paul McCartney and bandmate Denny Laine in tribute
    to the picturesque Kintyre peninsula in Argyll & Bute, Scotland,
    where McCartney had owned a home and recording studio since the late
    1960s.

    Lyrics:
    Oh mist rolling in from the sea,
    My desire is always to be here
    Oh mull of kintyre
    Far have I traveled and much have I seen
    Dark distant mountains with valleys of green.
    Past painted deserts the sunsets on fire
    As he carries me home to the mull of kintyre.

    Mull of kintyre
    Oh mist rolling in from the sea,
    My desire is always to be here
    Oh mull of kintyre

    Sweep through the heather like deer in the glen
    Carry me back to the days I knew then.
    Nights when we sang like a heavenly choir
    Of the life and the time of the mull of kintyre.

    Mull of kintyre
    Oh mist rolling in from the sea,
    My desire is always to be here
    Oh mull of kintyre

    Smiles in the sunshine
    And tears in the rain
    Still take me back to where my memories remain
    Flickering embers growing higher and higher
    As they carry me back to the mull of kintyre

    Mull of kintyre
    Oh mist rolling in from the sea,
    My desire is always to be here
    Oh mull of kintyre

    Mull of kintyre
    Oh mist rolling in from the sea,
    My desire is always to be here
    Oh mull of kintyre



    R.I.P. Chuck Berry - live in London 1972


     
    Charles
    Edward Anderson (Chuck Berry) - born 18 October 1926 in St Luis
    Missouri, passed away 18 March 2017 in Saint Charles, Missouri
    RIP Chuck Berry, have a good trip  






    Muddy Waters feat. Johnny Winter - Chicago Fest 1981


     
    Muddy Waters feat. Johnny Winter - Live At The Chicago Fest 1981






    Thursday, March 30, 2017

    The Laughing Policeman - Charles Jolly / Penrose



    The Laughing Policeman is a music hall song by Charles Jolly, the pseudonym
    of Charles Penrose. In 1922, Penrose made the first recording of this
    song, (Columbia Records FB 1184). The composition of the song is
    officially credited to his wife Mabel under the pseudonym "Billie Grey",
    however the music and melody are taken from The Laughing Song by George
    W. Johnson which was recorded in approximately 1901. 

    The Penroses wrote
    numerous other laughing songs (The Laughing Major, Curate,
    Steeplechaser, Typist, Lover, etc), but only The Laughing Policeman is
    remembered today, having sold over a million records. Its popularity
    continued into the 1970s, as it was a frequently-requested song on the
    BBC Radio 1 show Junior Choice.

    Wednesday, March 29, 2017

    Ray Charles - My Bonnie


    Ray Charles in a 1963 Brazilian Concert, with the original Raelettes & David Fathead Newman on lead Sax.


    Wednesday, February 22, 2017

    Hells Angels MC Westcoast - National Geographic Documentary 2017


      
    Published on Jan 22, 2017
    Hells Angels MC Westcoast

    • Category Comedy


    • Standard YouTube License



    Alcohol is a Solution



    Baffling, cunning and confusing addictive thinking ruins lives.
     

    Temptation



    Hallucinogenic drug helped problem drinkers


    Nature | News
    Retrospective analysis shows hallucinogenic drug helped problem drinkers.
     
    LSD blotter
    DEA/Science Faction/Corbis
    An analysis of old studies suggests LSD may have a role to play in treating alcoholism.
    The powerful hallucinogen LSD (lysergic acid diethylamide) has potential as a treatment for alcoholism, according to a retrospective analysis of studies published in the late 1960s and early 1970s.

    The study1, by neuroscientist Teri Krebs and clinical psychologist Pål-Ørjan Johansen of the Norwegian University of Science and Technology in Trondheim, is the first-ever quantitative meta-analysis of LSD–alcoholism clinical trials. The researchers sifted through thousands of records to collect data from randomized, double-blind trials that compared one dose of LSD to a placebo.

    Of 536 participants in six trials, 59% of people receiving LSD reported lower levels of alcohol misuse, compared to 38% of people who received a placebo. 

    “We were surprised that the effect was so clear and consistent,” says Krebs. She says that the problem with most studies done at that time was that there were too few participants, which limited statistical power. “But when you combine the data in a meta-analysis, we have more than 500 patients and there is definitely an effect,” she says. 

    In general, the reported benefits lasted three to six months. Their findings are published today in the Journal of Psychopharmacology.

    Psychedelics were promoted by psychiatrists in the 1950s as having a range of medical uses — to treat conditions such as schizophrenia, for example — before political pressures in the United States and elsewhere largely ended the work.

    “Alcoholism was considered one of the most promising clinical applications for LSD,” says Johansen.

    Alcoholics Anonymous co-founder Bill Wilson is said to have espoused the benefits of LSD
    in the book Pass It On: The Story of Bill Wilson and How the AA Message Reached the World.

    In the last decade or so, however, a new generation of researchers have been interested in harnessing the therapeutic benefits of illicit drugs — such as (MDMA or ecstasy) 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) for post-traumatic stress disorder, ayahuasca for drug and alcohol dependency, and psilocybin, the active ingredient in hallucinogenic mushrooms, for smoking cessation.

    The snow globe of perception?

    How psychedelics exert such effects, especially after a single dose, remains unclear. LSD and its chemical cousins share structural similarities with the neurotransmitter serotonin, which is linked to many aspects of mood, memory and pleasure. These psychedelics also bind the same receptor sites in the brain as serotonin, but there the similarity may end — studies have shown that the hallucinogens elicit chemical cascades different from other compounds that bind at the same receptor2. To complicate matters further, LSD also acts at other receptors3.

    For the moment, studying human behavioural responses rather than brain chemistry may be more helpful in understanding how the drugs work.

    Robin Carhart-Harris, a psychopharmacologist at Imperial College London who has researched how psilocybin could treat depression, says that psychedelics must work at both biological and psychological levels. “Psychedelics probably work in addiction by making the brain function more chaotically for a period — a bit like shaking up a snow globe — weakening reinforced brain connections and dynamics,” he says.

    Roland Griffiths, a behavioural biologist at the Johns Hopkins University School of Medicine in Baltimore, Maryland, is investigating the influence of psilocybin on smoking cessation, and says that psychedelics sometimes give rise to distinctive, insightful experiences that can produce enduring positive changes in attitude, mood and behaviour.

    “This is impressive and important work,” says Matthew Johnson, a psychiatrist also at Johns Hopkins University who is now running a small trial looking at the effectiveness of psilocybin to treat nicotine addiction.

    “Although this meta-analysis does not replace the need to test the approach in new, well-designed and rigorous clinical trials, it puts some more muscle behind the interpretation that the older literature shows hints that psychedelic therapy might really help addiction.”

    However, Ken Checinski, a consultant addiction psychiatrist and independent researcher based in London, says that although the results are exciting, no pharmacological treatment should be seen as a magic bullet and that modern therapeutic techniques have improved.
     
    “The included LSD trials pre-date the use of psychological techniques such as motivational interviewing and cognitive behaviour therapy,” he says.
    Nature
    doi:10.1038/nature.2012.10200

    References

    1. Krebs, T. S. & Johansen, P-O. J. Psychopharmacol. http://dx.doi.org/10.1177/0269881112439253 (2012).
    2. González-Maeso, J. et al. J. Neurosci. 23, 88368843 (2003).
    3. Halberstadt, A. L. & Geyer, M. A. Neuropharmacology 61, 364381 (2011).
     

    Tuesday, February 21, 2017

    Steppenwolf - The Pusher



      
    LYRICS:



    You know I smoked a lot of grass.

    Oh Lord! I popped a lot of pills.

    But I've never touched nothin'

    That my spirit couldn't kill.

    You know I've seen a lot of people walking 'round

    With tombstones in their eyes.

    But the pusher don't care

    If you live -- or if you die.

    God Damn! The pusher.

    God Damn! The pusher.

    I said God Damn! God damn the pusher man.

    You know the dealer, the dealer is a man

    With a lump of grass in his hand.

    But the pusher is a monster

    Not a natural man.

    The dealer for a nickel

    Goin to sell you lots of sweet dreams.

    Ah...but the pusher will ruin your body;

    Lord he'll leave your mind to scream.

    God Damn! The pusher.

    God Damn! God damn the pusher.

    I said God Damn! God damn the pusher man.

    Well now if I were the president of this land

    You know I'd declare total war on the pusher man.

    I'd cut him if he stands, and I'd shoot him if he run,

    And I'd kill him with my bible, and my razor and my gun....

    GOD DAMN! The pusher

    God damn the pusher.

    I said God damn! God damn the pusher man!